Associated Publications:

Publications 2014:

91. K. Zhang, J. Zhang, Z. G. Gao, D. Zhang, L. Zhu, G. W. Han, S. M. Moss, S. Paoletta, E. Kiselev, W. Lu, G. Fenalti, W. Zhang, C. Müller, H. Yang, H. Jiang, V. Cherezov, V. Katritch, K. A. Jacobson, R. C. Stevens, B. Wu and Q. Zhao (2014) Structure of the human P2Y12 receptor in complex with an antithrombotic drug Nature 509: 115-118 ;
90. J. Zhang, K. Zhang, Z. G. Gao, S. Paoletta, D. Zhang, G. W. Han, T. Li, L. Ma, W. Zhang, C. Müller, H. Yang, H. Jiang, V. Cherezov, V. Katritch, K. A. Jacobson, R. C. Stevens, B. Wu and Q. Zhao (2014) Agonist-bound structure of the human P2Y12 receptor Nature 509: 119-122 ;
89. H. Wu, C. Wang, K. J. Gregory, G. W. Han, H. P. Cho, Y. Xia, C. M. Niswender, V. Katritch, J. Meiler, V. Cherezov, P. J. Conn and R. C. Stevens (2014) Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator Science 344: 58-64 ;
88. U. Weierstall, D. James, C. Wang, T. A. White, D. Wang, W. Liu, J. C. Spence, R. Bruce Doak, G. Nelson, P. Fromme, R. Fromme, I. Grotjohann, C. Kupitz, N. A. Zatsepin, H. Liu, S. Basu, D. Wacker, G. W. Han, V. Katritch, S. Boutet, M. Messerschmidt, G. J. Williams, J. E. Koglin, M. Marvin Seibert, M. Klinker, C. Gati, R. L. Shoeman, A. Barty, H. N. Chapman, R. A. Kirian, K. R. Beyerlein, R. C. Stevens, D. Li, S. T. Shah, N. Howe, M. Caffrey and V. Cherezov (2014) Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography Nat Commun 5: 3309 ;
87. F. M. McRobb, V. Sahagun, I. Kufareva and R. Abagyan (2014) In silico analysis of the conservation of human toxicity and endocrine disruption targets in aquatic species Environ Sci Technol 48: 1964-72 ;
86. D. P. Kennedy, F. M. McRobb, S. A. Leonhardt, M. Purdy, H. Figler, M. A. Marshall, M. Chordia, R. Figler, J. Linden, R. Abagyan and M. Yeager (2014) The second extracellular loop of the adenosine A1 receptor mediates activity of allosteric enhancers Mol Pharmacol 85: 301-9 ;
85. V. Katritch, G. Fenalti, E. E. Abola, B. L. Roth, V. Cherezov and R. C. Stevens (2014) Allosteric sodium in class A GPCR signaling Trends Biochem Sci
84. K. Hollenstein, C. de Graaf, A. Bortolato, M. W. Wang, F. H. Marshall and R. C. Stevens (2014) Insights into the structure of class B GPCRs Trends Pharmacol Sci 35: 12-22 ;
83. G. Fenalti, P. M. Giguere, V. Katritch, X. P. Huang, A. A. Thompson, V. Cherezov, B. L. Roth and R. C. Stevens (2014) Molecular control of delta-opioid receptor signalling Nature 506: 191-6 ;

Publications 2013:

82. D. R. Webb, T. M. Handel, A. Kretz-Rommel and R. C. Stevens (2013) Opportunities for functional selectivity in GPCR antibodies Biochem Pharmacol 85: 147-52 ;
81. C. Wang, H. Wu, V. Katritch, G. W. Han, X. P. Huang, W. Liu, F. Y. Siu, B. L. Roth, V. Cherezov and R. C. Stevens (2013) Structure of the human smoothened receptor bound to an antitumour agent Nature 497: 338-43 ;
80. C. Wang, Y. Jiang, J. Ma, H. Wu, D. Wacker, V. Katritch, G. W. Han, W. Liu, X. P. Huang, E. Vardy, J. D. McCorvy, X. Gao, X. E. Zhou, K. Melcher, C. Zhang, F. Bai, H. Yang, L. Yang, H. Jiang, B. L. Roth, V. Cherezov, R. C. Stevens and H. E. Xu (2013) Structural basis for molecular recognition at serotonin receptors Science 340: 610-4 ;
79. D. Wacker, C. Wang, V. Katritch, G. W. Han, X. P. Huang, E. Vardy, J. D. McCorvy, Y. Jiang, M. Chu, F. Y. Siu, W. Liu, H. E. Xu, V. Cherezov, B. L. Roth and R. C. Stevens (2013) Structural features for functional selectivity at serotonin receptors Science 340: 615-9 ;
78. E. Vardy, P. D. Mosier, K. J. Frankowski, H. Wu, V. Katritch, R. B. Westkaemper, J. Aube, R. C. Stevens and B. L. Roth (2013) Chemotype-selective Modes of Action of kappa-Opioid Receptor Agonists J Biol Chem 288: 34470-83 ;
77. Q. Tan, Y. Zhu, J. Li, Z. Chen, G. W. Han, I. Kufareva, T. Li, L. Ma, G. Fenalti, J. Li, W. Zhang, X. Xie, H. Yang, H. Jiang, V. Cherezov, H. Liu, R. C. Stevens, Q. Zhao and B. Wu (2013) Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex Science 341: 1387-90 ;
76. R. C. Stevens, V. Cherezov, V. Katritch, R. Abagyan, P. Kuhn, H. Rosen and K. Wuthrich (2013) The GPCR Network: a large-scale collaboration to determine human GPCR structure and function Nat Rev Drug Discov 12: 25-34 ;
75. F. Y. Siu, M. He, C. de Graaf, G. W. Han, D. Yang, Z. Zhang, C. Zhou, Q. Xu, D. Wacker, J. S. Joseph, W. Liu, J. Lau, V. Cherezov, V. Katritch, M. W. Wang and R. C. Stevens (2013) Structure of the human glucagon class B G-protein-coupled receptor Nature 499: 444-9 ;
74. M. Rueda, M. Orozco, M. Totrov and R. Abagyan (2013) BioSuper: a web tool for the superimposition of biomolecules and assemblies with rotational symmetry BMC Struct Biol 13: 32 ;
73. H. Rosen, R. C. Stevens, M. Hanson, E. Roberts and M. B. Oldstone (2013) Sphingosine-1-phosphate and its receptors: structure, signaling, and influence Annu Rev Biochem 82: 637-62 ;
72. U. Pieper, A. Schlessinger, E. Kloppmann, G. A. Chang, J. J. Chou, M. E. Dumont, B. G. Fox, P. Fromme, W. A. Hendrickson, M. G. Malkowski, D. C. Rees, D. L. Stokes, M. H. Stowell, M. C. Wiener, B. Rost, R. M. Stroud, R. C. Stevens and A. Sali (2013) Coordinating the impact of structural genomics on the human alpha-helical transmembrane proteome Nat Struct Mol Biol 20: 135-8 ;
71. M. O'Hayre, J. Vazquez-Prado, I. Kufareva, E. W. Stawiski, T. M. Handel, S. Seshagiri and J. S. Gutkind (2013) The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer Nat Rev Cancer 13: 412-24 ;
70. W. Liu, D. Wacker, C. Gati, G. W. Han, D. James, D. Wang, G. Nelson, U. Weierstall, V. Katritch, A. Barty, N. A. Zatsepin, D. Li, M. Messerschmidt, S. Boutet, G. J. Williams, J. E. Koglin, M. M. Seibert, C. Wang, S. T. Shah, S. Basu, R. Fromme, C. Kupitz, K. N. Rendek, I. Grotjohann, P. Fromme, R. A. Kirian, K. R. Beyerlein, T. A. White, H. N. Chapman, M. Caffrey, J. C. Spence, R. C. Stevens and V. Cherezov (2013) Serial femtosecond crystallography of G protein-coupled receptors Science 342: 1521-4 ;
69. J. R. Lane, P. Chubukov, W. Liu, M. Canals, V. Cherezov, R. Abagyan, R. C. Stevens and V. Katritch (2013) Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors Mol Pharmacol 84: 794-807 ;
68. I. Kufareva, B. Stephens, C. T. Gilliland, B. Wu, G. Fenalti, D. Hamel, R. C. Stevens, R. Abagyan and T. M. Handel (2013) A novel approach to quantify G-protein-coupled receptor dimerization equilibrium using bioluminescence resonance energy transfer Methods Mol Biol 1013: 93-127 ;
67. V. Katritch, V. Cherezov and R. C. Stevens (2013) Structure-Function of the G Protein-Coupled Receptor Superfamily Annu Rev Pharmacol Toxicol 53: 531-556 ;
66. K. Hollenstein, C. de Graaf, A. Bortolato, M. W. Wang, F. H. Marshall and R. C. Stevens (2013) Insights into the structure of class B GPCRs Trends Pharmacol Sci
65. K. G. Harikumar, E. E. Cawston, P. C. Lam, A. Patil, A. Orry, B. R. Henke, R. Abagyan, A. Christopoulos, P. M. Sexton and L. J. Miller (2013) Molecular basis for benzodiazepine agonist action at the type 1 cholecystokinin receptor J Biol Chem 288: 21082-95 ;
64. H. Gutierrez-de-Teran, A. Massink, D. Rodriguez, W. Liu, G. W. Han, J. S. Joseph, I. Katritch, L. H. Heitman, L. Xia, A. P. Ijzerman, V. Cherezov, V. Katritch and R. C. Stevens (2013) The Role of a Sodium Ion Binding Site in the Allosteric Modulation of the A2A Adenosine G Protein-Coupled Receptor Structure 21: 2175-85 ;
63. M. Gabrielsen, K. Wolosewicz, A. Zawadzka, J. Kossakowski, G. Nowak, M. Wolak, K. Stachowicz, A. Siwek, A. W. Ravna, I. Kufareva, L. Kozerski, E. Bednarek, J. Sitkowski, W. Bocian, R. Abagyan, A. J. Bojarski, I. Sylte and Z. Chilmonczyk (2013) Synthesis, antidepressant evaluation and docking studies of long-chain alkylnitroquipazines as serotonin transporter inhibitors Chem Biol Drug Des 81: 695-706 ;
62. I. Coin, V. Katritch, T. Sun, Z. Xiang, F. Y. Siu, M. Beyermann, R. C. Stevens and L. Wang (2013) Genetically Encoded Chemical Probes in Cells Reveal the Binding Path of Urocortin-I to CRF Class B GPCR Cell 155: 1258-69 ;
61. C. Bissig, M. Lenoir, M. C. Velluz, I. Kufareva, R. Abagyan, M. Overduin and J. Gruenberg (2013) Viral infection controlled by a calcium-dependent lipid-binding module in ALIX Dev Cell 25: 364-73 ;

Publications 2012:

60. H. Wu, D. Wacker, M. Mileni, V. Katritch, G. W. Han, E. Vardy, W. Liu, A. A. Thompson, X. P. Huang, F. I. Carroll, S. W. Mascarella, R. B. Westkaemper, P. D. Mosier, B. L. Roth, V. Cherezov and R. C. Stevens (2012) Structure of the human kappa-opioid receptor in complex with JDTic Nature 485: 327-332 ;
59. D. K. Tosh, K. Phan, Z. G. Gao, A. A. Gakh, F. Xu, F. Deflorian, R. Abagyan, R. C. Stevens, K. A. Jacobson and V. Katritch (2012) Optimization of adenosine 5'-carboxamide derivatives as adenosine receptor agonists using structure-based ligand design and fragment screening J Med Chem 55: 4297-308 ;
58. A. A. Thompson, W. Liu, E. Chun, V. Katritch, H. Wu, E. Vardy, X. P. Huang, C. Trapella, R. Guerrini, G. Calo, B. L. Roth, V. Cherezov and R. C. Stevens (2012) Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic Nature 485: 395-9 ;
57. M. A. Neves, M. Yeager and R. Abagyan (2012) Unusual arginine formations in protein function and assembly: rings, strings, and stacks J Phys Chem B 116: 7006-13 ;
56. M. A. Neves, M. Totrov and R. Abagyan (2012) Docking and scoring with ICM: the benchmarking results and strategies for improvement J Comput Aided Mol Des 26: 675-86 ;
55. W. Liu, E. Chun, A. A. Thompson, P. Chubukov, F. Xu, V. Katritch, G. W. Han, C. B. Roth, L. H. Heitman, I. J. AP, V. Cherezov and R. C. Stevens (2012) Structural basis for allosteric regulation of GPCRs by sodium ions Science 337: 232-6 ;
54. J. J. Liu, R. Horst, V. Katritch, R. C. Stevens and K. Wuthrich (2012) Biased signaling pathways in beta2-adrenergic receptor characterized by 19F-NMR Science 335: 1106-10 ; 10.1126/science.1215802 " target="_blank">
53. V. Katritch, V. Cherezov and R. C. Stevens (2012) Diversity and modularity of G protein-coupled receptor structures Trends Pharmacol Sci 33: 17-27 ; 10.1016/j.tips.2011.09.003 " target="_blank">
52. M. A. Hanson, C. B. Roth, E. Jo, M. T. Griffith, F. L. Scott, G. Reinhart, H. Desale, B. Clemons, S. M. Cahalan, S. C. Schuerer, M. G. Sanna, G. W. Han, P. Kuhn, H. Rosen and R. C. Stevens (2012) Crystal structure of a lipid G protein-coupled receptor Science 335: 851-5 ; 10.1126/science.1215904 " target="_blank">
51. F. Deflorian, T. S. Kumar, K. Phan, Z. G. Gao, F. Xu, H. Wu, V. Katritch, R. C. Stevens and K. A. Jacobson (2012) Evaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound A(2)A adenosine receptor J Med Chem 55: 538-52 ;
50. E. Chun, A. A. Thompson, W. Liu, C. B. Roth, M. T. Griffith, V. Katritch, J. Kunken, F. Xu, V. Cherezov, M. A. Hanson and R. C. Stevens (2012) Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors Structure 20: 967-76 ;
49. E. E. Cawston, P. C. Lam, K. G. Harikumar, M. Dong, A. M. Ball, M. L. Augustine, E. Akgun, P. S. Portoghese, A. Orry, R. Abagyan, P. M. Sexton and L. J. Miller (2012) Molecular basis for binding and subtype selectivity of 1,4-benzodiazepine antagonist ligands of the cholecystokinin receptor J Biol Chem 287: 18618-35 ; 10.1074/jbc.M111.335646 " target="_blank">

Publications 2011:

48. F. Xu, H. Wu, V. Katritch, G. W. Han, K. A. Jacobson, Z. G. Gao, V. Cherezov and R. C. Stevens (2011) Structure of an agonist-bound human A2A adenosine receptor Science 332: 322-7 ; 10.1126/science.1202793 " target="_blank">
47. T. Shimamura, M. Shiroishi, S. Weyand, H. Tsujimoto, G. Winter, V. Katritch, R. Abagyan, V. Cherezov, W. Liu, G. W. Han, T. Kobayashi, R. C. Stevens and S. Iwata (2011) Structure of the human histamine H(1) receptor complex with doxepin Nature 475: 65-70 ;
46. V. Katritch, I. Kufareva and R. Abagyan (2011) Structure based prediction of subtype-selectivity for adenosine receptor antagonists Neuropharmacology 60: 108-15 ; 10.1016/j.neuropharm.2010.07.009 " target="_blank">

Publications 2010:

45. B. Wu, E. Y. Chien, C. D. Mol, G. Fenalti, W. Liu, V. Katritch, R. Abagyan, A. Brooun, P. Wells, F. C. Bi, D. J. Hamel, P. Kuhn, T. M. Handel, V. Cherezov and R. C. Stevens (2010) Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists Science 330: 1066-71 ; 10.1126/science.1194396 " target="_blank">
44. C. G. Tate and R. C. Stevens (2010) Growth and excitement in membrane protein structural biology Curr Opin Struct Biol 20: 399-400 ; 10.1016/j.sbi.2010.07.002 " target="_blank">
43. R. C. Stevens, J. Sancho and A. Martinez (2010) Rescue of misfolded proteins and stabilization by small molecules Methods Mol Biol 648: 313-24 ;
42. F. Y. Siu and R. C. Stevens (2010) RAMP-ing up class-B GPCR ECD structural coverage Structure 18: 1067-8 ; 10.1016/j.str.2010.08.004 " target="_blank">
41. M. Michino, J. Chen, R. C. Stevens and C. L. Brooks, 3rd (2010) FoldGPCR: structure prediction protocol for the transmembrane domain of G protein-coupled receptors from class A Proteins 78: 2189-201 ;
40. W. Liu, M. A. Hanson, R. C. Stevens and V. Cherezov (2010) LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment Biophys J 98: 1539-48 ; 10.1016/j.bpj.2009.12.4296 " target="_blank">
39. D. J. Kissick, E. J. Gualtieri, G. J. Simpson and V. Cherezov (2010) Nonlinear optical imaging of integral membrane protein crystals in lipidic mesophases Anal Chem 82: 491-7 ;
38. V. Katritch, V. P. Jaakola, J. R. Lane, J. Lin, A. P. Ijzerman, M. Yeager, I. Kufareva, R. C. Stevens and R. Abagyan (2010) Structure-Based Discovery of Novel Chemotypes for Adenosine A(2A) Receptor Antagonists J Med Chem 53: 1799-1809 ;
37. W. X. Hong, K. A. Baker, X. Ma, R. C. Stevens, M. Yeager and Q. Zhang (2010) Design, synthesis, and properties of branch-chained maltoside detergents for stabilization and crystallization of integral membrane proteins: human connexin 26 Langmuir 26: 8690-6 ;
36. E. Y. Chien, W. Liu, Q. Zhao, V. Katritch, G. W. Han, M. A. Hanson, L. Shi, A. H. Newman, J. A. Javitch, V. Cherezov and R. C. Stevens (2010) Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist Science 330: 1091-5 ; 10.1126/science.1197410 " target="_blank">

Publications 2009:

35. P. Stanczak, R. Horst, P. Serrano and K. Wuthrich (2009) NMR characterization of membrane protein-detergent micelle solutions by use of microcoil equipment J Am Chem Soc 131: 18450-6 ;
34. M. Michino, E. Abola, C. L. Brooks, 3rd, J. S. Dixon, J. Moult and R. C. Stevens (2009) Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008 Nat Rev Drug Discov 8: 455-63 ; 10.1038/nrd2877 " target="_blank">
33. V. Katritch, K. A. Reynolds, V. Cherezov, M. A. Hanson, C. B. Roth, M. Yeager and R. Abagyan (2009) Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes J Mol Recognit 22: 307-18 ;
32. V. P. Jaakola, Stevens, R.C. (2009) G Protein-Coupled Receptors Handbook of Cell Signalling
31. M. A. Hanson and R. C. Stevens (2009) Discovery of new GPCR biology: one receptor structure at a time Structure 17: 8-14 ; 10.1016/j.str.2008.12.003 " target="_blank">
30. V. Cherezov, M. A. Hanson, M. T. Griffith, M. C. Hilgart, R. Sanishvili, V. Nagarajan, S. Stepanov, R. F. Fischetti, P. Kuhn and R. C. Stevens (2009) Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam J R Soc Interface 6 Suppl 5: S587-97 ; 10.1098/rsif.2009.0142.focus " target="_blank">
29. M. Caffrey and V. Cherezov (2009) Crystallizing membrane proteins using lipidic mesophases Nat Protoc 4: 706-31 ; 10.1038/nprot.2009.31 " target="_blank">

Publications 2008:

28. Q. Zhang, R. Horst, M. Geralt, X. Ma, W. X. Hong, M. G. Finn, R. C. Stevens and K. Wuthrich (2008) Microscale NMR screening of new detergents for membrane protein structural biology J Am Chem Soc 130: 7357-63 ;
27. C. B. Roth, M. A. Hanson and R. C. Stevens (2008) Stabilization of the human beta2-adrenergic receptor TM4-TM3-TM5 helix interface by mutagenesis of Glu122(3.41), a critical residue in GPCR structure J Mol Biol 376: 1305-19 ; 10.1016/j.jmb.2007.12.028 " target="_blank">
26. J. D. Ng, R. C. Stevens and P. Kuhn (2008) Protein crystallization in restricted geometry: advancing old ideas for modern times in structural proteomics Methods Mol Biol 426: 363-76 ;
25. J. D. Ng, P. J. Clark, R. C. Stevens and P. Kuhn (2008) In situ X-ray analysis of protein crystals in low-birefringent and X-ray transmissive plastic microchannels Acta Crystallogr D Biol Crystallogr 64: 189-97 ; 10.1107/S0907444907060064 " target="_blank">
24. V. P. Jaakola, M. T. Griffith, M. A. Hanson, V. Cherezov, E. Y. Chien, J. R. Lane, A. P. Ijzerman and R. C. Stevens (2008) The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist Science 10.1126/science.1164772 " target="_blank">
23. M. A. Hanson, V. Cherezov, M. T. Griffith, C. B. Roth, V. P. Jaakola, E. Y. Chien, J. Velasquez, P. Kuhn and R. C. Stevens (2008) A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor Structure 16: 897-905 ; 10.1016/j.str.2008.05.001 " target="_blank">
22. V. Cherezov, J. Liu, M. Griffith, M. A. Hanson and R. C. Stevens (2008) LCP-FRAP Assay for Pre-Screening Membrane Proteins for in Meso Crystallization Cryst Growth Des 8: 4307-4315 ;
21. G. A. Asmar-Rovira, A. M. Asseo-Garcia, O. Quesada, M. A. Hanson, A. Cheng, C. Nogueras, J. A. Lasalde-Dominicci and R. C. Stevens (2008) Biophysical and Ion Channel Functional Characterization of the Torpedo californica Nicotinic Acetylcholine Receptor in Varying Detergent-Lipid Environments J Membr Biol 223: 13-26 ;
20. A. I. Alexandrov, M. Mileni, E. Y. Chien, M. A. Hanson and R. C. Stevens (2008) Microscale fluorescent thermal stability assay for membrane proteins Structure 16: 351-9 ;
19. E. E. Abola and R. C. Stevens (2008) The importance of target selection strategies in structural biology J. L. Sussman and I. Silman Structural proteomics and its impact on the life sciences Singapore World Scientific Publishing Co. 1-28

Publications 2007:

18. Q. Zhang, X. Ma, A. Ward, W. X. Hong, V. P. Jaakola, R. C. Stevens, M. G. Finn and G. Chang (2007) Designing facial amphiphiles for the stabilization of integral membrane proteins Angew Chem Int Ed Engl 46: 7023-5 ;
17. R. C. Stevens and J. R. Yates, 3rd (2007) You say functional, I say structural J Proteome Res 6: 927 ;
16. R. C. Stevens (2007) Generation of protein structures for the 21(st) century Structure 15: 1517-9 ; 10.1016/j.str.2007.11.003 " target="_blank">
15. D. M. Rosenbaum, V. Cherezov, M. A. Hanson, S. G. Rasmussen, F. S. Thian, T. S. Kobilka, H. J. Choi, X. J. Yao, W. I. Weis, R. C. Stevens and B. K. Kobilka (2007) GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function Science 318: 1266-73 ; 10.1126/science.1150609 " target="_blank">
14. M. A. Hanson, A. Brooun, K. A. Baker, V. P. Jaakola, C. Roth, E. Y. Chien, A. Alexandrov, J. Velasquez, L. Davis, M. Griffith, K. Moy, B. K. Ganser-Pornillos, Y. Hua, P. Kuhn, S. Ellis, M. Yeager and R. C. Stevens (2007) Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression Protein Expr Purif 56: 85-92 ; 10.1016/j.pep.2007.06.003 " target="_blank">
13. V. Cherezov, D. M. Rosenbaum, M. A. Hanson, S. G. Rasmussen, F. S. Thian, T. S. Kobilka, H. J. Choi, P. Kuhn, W. I. Weis, B. K. Kobilka and R. C. Stevens (2007) High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor Science 318: 1258-65 ; 10.1126/science.1150577 " target="_blank">
12. E. Abola, D. D. Carlton, P. Kuhn and R. C. Stevens (2007) Five years of increasing structural biology throughput. A retrospective analysis H. Jhoti and A. Leach Structure based drug discovery The Netherlands Springer-Verlag 1-26

Publications 2005:

10. M. K. Yadav, C. J. Gerdts, R. Sanishvili, W. W. Smith, L. S. Roach, R. F. Ismagilov, P. Kuhn and R. C. Stevens (2005) In situ data collection and structure refinement from microcapillary protein crystallization J Appl Crystallogr 38: 900-905 ;
9. W. Peti, R. Page, K. Moy, M. O'Neil-Johnson, I. A. Wilson, R. C. Stevens and K. Wuthrich (2005) Towards miniaturization of a structural genomics pipeline using micro-expression and microcoil NMR J Struct Funct Genomics 6: 259-67 ;
8. R. Page, W. Peti, I. A. Wilson, R. C. Stevens and K. Wuthrich (2005) NMR screening and crystal quality of bacterially expressed prokaryotic and eukaryotic proteins in a structural genomics pipeline Proc Natl Acad Sci U S A 102: 1901-5 ; 10.1073/pnas.0408490102 " target="_blank">
7. R. Page, A. M. Deacon, S. A. Lesley and R. C. Stevens (2005) Shotgun crystallization strategy for structural genomics II: crystallization conditions that produce high resolution structures for T. maritima proteins J Struct Funct Genomics 6: 209-17 ;
6. F. Katzen, G. Chang and W. Kudlicki (2005) The past, present and future of cell-free protein synthesis Trends Biotechnol 23: 150-6 ; 10.1016/j.tibtech.2005.01.003 " target="_blank">
5. B. Collins, R. C. Stevens and R. Page (2005) Crystallization Optimum Solubility Screening: using crystallization results to identify the optimal buffer for protein crystal formation Acta Crystallogr Sect F Struct Biol Cryst Commun 61: 1035-8 ; 10.1107/S1744309105035244 " target="_blank">

Publications 2004:

4. R. Page and R. C. Stevens (2004) Crystallization data mining in structural genomics: using positive and negative results to optimize protein crystallization screens Methods 34: 373-89 ;
3. R. Page, K. Moy, E. C. Sims, J. Velasquez, B. McManus, C. Grittini, T. L. Clayton and R. C. Stevens (2004) Scalable high-throughput micro-expression device for recombinant proteins Biotechniques 37: 364, 366, 368 passim ;
2. J. M. Canaves, R. Page, I. A. Wilson and R. C. Stevens (2004) Protein biophysical properties that correlate with crystallization success in Thermotoga maritima: maximum clustering strategy for structural genomics J Mol Biol 344: 977-91 ; 10.1016/j.jmb.2004.09.076 " target="_blank">
1. M. H. Bracey, B. F. Cravatt and R. C. Stevens (2004) Structural commonalities among integral membrane enzymes FEBS Lett 567: 159-65 ;